Nucleosides and Analogues
Cambridge Isotope Laboratories Adenosine phosphoramidite (U-13C10 98%) CP 95% 50 mg
Adenosine phosphoramidite (U-13C10 98%) CP 95% 50 mg
Medchemexpress LLC Adenosine antagonist-1 | 431040-19-6 | 99.8% | 359.41 g/mol | C18H13N7S | 25 MG
Adenosine antagonist-1 is a small-molecule adenosine A3 receptor (A3R) antagonist reported to have anti-inflammatory activity for in vitro and preclinical research. The compound is supplied as a white to off-white solid with molecular formula C18H13N7S and molecular weight 359.41 g/mol. Typical purity is 99.79% and the material is provided in milligram-scale quantities for laboratory studies.
- Acts as an adenosine A3 receptor antagonist with anti-inflammatory activity.
- High chemical purity (99.79%) suitable for research applications.
- Molecular formula C18H13N7S; molecular weight 359.41 g/mol.
- Available in milligram-scale quantities for in vitro and preclinical studies.
- Supplied as a white to off-white solid for easier handling and storage.
Cambridge Isotope Laboratories Guanosine phosphoramidite (U-13C10 98%) CP 95% 10 mg
Guanosine phosphoramidite (U-13C10 98%) CP 95% 10 mg
Selleck Chemical LLC Adenosine S1647-10mM/1mL
Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a -N9-glycosidic bond
Medchemexpress LLC ATP dimagnesium | 74804-12-9 | 98.0% | 100 MG
ATP (Adenosine 5'-triphosphate) dimagnesium is a vital element in energy storage and metabolism within living organisms. It supplies the metabolic energy required for metabolic pumps and functions as a coenzyme in cells. Additionally, ATP dimagnesium acts as a significant endogenous signaling molecule involved in immunity and inflammation.
- A central component of energy storage and metabolism in vivo.
- Provides metabolic energy to drive metabolic pumps.
- Serves as a coenzyme in cells.
- An important endogenous signaling molecule in immunity and inflammation.
- For research use only.
Medchemexpress LLC Guanosine 5'-diphosphate sodium | 43139-22-6 | 99.9% | 465.18 | 500 MG
Guanosine 5'-diphosphate sodium is a nucleoside diphosphate known for activating adenosine 5'-triphosphate-sensitive K+ channels. It acts as an iron mobilizer by forming a complex with hepcidin, which inhibits the hepcidin-ferroportin (FPN) interaction and modulates the IL-6/Stat-3 pathway. This compound has been shown to ameliorate Turpentine-induced anemia of inflammation (AI) in mice, especially when combined with FeSO4, highlighting its utility in AI research.
- Activates ATP-sensitive K+ channels.
- Mobilizes iron by inhibiting hepcidin-FPN interaction.
- Modulates IL-6/Stat-3 pathway.
- Ameliorates anemia of inflammation (AI).
- Increases iron absorption and FPN levels in liver, spleen, and enterocytes.
- Reduces iron storage ferritin and Stat-3 phosphorylation.
- Decreases Hamp mRNA and hepcidin expression.
Apexbio Technology LLC 2'-O-Methyl-N6-Methyl-ATP 100ul (100 mM)
2p-O-Methyl-N6-Methyl-ATP is a chemically modified ATP analog bearing methyl substitutions at the N6 position of adenine and the 2 -hydroxyl group of the ribose sugar 2p-O-Methyl-N6-Methyl-ATP is designed to facilitate the study of RNA methylation processes and RNA protein interactions supporting the mechanistic exploration of RNA-modifying enzymes and epigenetic regulatory pathways Based on these properties 2p-O-Methyl-N6-Methyl-ATP holds research potential in investigations of ligand RNA interactions and drug discovery applications targeting RNA-related biological processes
Medchemexpress LLC Adenosine 5'-(tetrahydrogen triphosphate), sodium salt (1:2) | 987-65-5 | 1 ML
Adenosine 5'-(tetrahydrogen triphosphate), sodium salt (1:2) | 987-65-5 | 1 ML
Medchemexpress LLC Adenosine 5'-monophosphate | 61-19-8 | MFCD00149360 | 99.8% | 347.22 | C10H14N5O7P | 10 MG
Adenosine 5'-monophosphate (AMP) is a nucleotide involved in cellular energy transfer and signal transduction. This research-grade biochemical is supplied as a solid or solution and is intended for in vitro research applications; the manufacturer lists high purity and molecular weight of 347.22 g/mol.
- High purity (99.8%) suitable for research use
- Defined molecular weight of 347.22 g/mol
- Available as solid and as DMSO solution for flexible use
- Commonly used in biochemical assays and receptor pharmacology studies
- Provided with supporting documentation such as datasheets and COA when available
Medchemexpress LLC Adenosine 5'-monophosphate (disodium) | 4578-31-8 | 99.6% | 391.18 | 500 MG
Adenosine 5'-monophosphate disodium is an orally active purine nucleotide that participates in ATP metabolism. It is also a ligand for the adenosine 2B receptor. It can activate AMPK in skeletal muscle, ameliorating insulin resistance and impaired glucose metabolism. This product can be used for research on diabetes.
- Orally active purine nucleotide
- Participates in ATP metabolism
- Ligand for adenosine 2B receptor
- Activates AMPK in skeletal muscle
- Ameliorates insulin resistance and impaired glucose metabolism
- Can be used for research of diabetes
![eMolecules Medchem Express / Rp-cAMPS (sodium salt) / 1mg / 632433127 / HY-100530D / / 142439-94-9 / [null] / 367.250 / C10H11N5NaO5PS](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502472106.JPG-250.jpg)
eMolecules Medchem Express / Rp-cAMPS (sodium salt) / 1mg / 632433127 / HY-100530D / / 142439-94-9 / [null] / 367.250 / C10H11N5NaO5PS
Medchem Express / Rp-cAMPS (sodium salt) / 1mg / 632433127 / HY-100530D / / 142439-94-9 / [null] / 367.250 / C10H11N5NaO5PS
Medchemexpress LLC Rp-cAMPS sodium salt | 142439-94-9 | 99.7% | 367.25 | C10H11N5NaO5PS | 5 MG
Rp-cAMPS sodium salt is a cAMP analog that competitively antagonizes cAMP-dependent protein kinase A (PKA) I and II and is resistant to hydrolysis by phosphodiesterases, intended for biochemical and cell signaling research applications.
- High purity (≈99.7%) suitable for biochemical assays.
- Molecular formula C10H11N5NaO5PS and molecular weight 367.25 g/mol.
- Resistant to hydrolysis by phosphodiesterases.
- Reported Ki values ~6.05 μM (PKA I) and ~9.75 μM (PKA II).
- Solid, white to pink appearance; available as solid or solution (10 mM in DMSO).
- Storage: -20°C sealed; in solvent -80°C (6 months) or -20°C (1 month).
Selleck Chemical LLC Lamivudine S1706-10mM/1mL
Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor used for treatment of chronic HBV and HIV/AIDS It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase
Apexbio Technology LLC Lamivudine 134678-17-4 50mg
Lamivudine is a nucleoside analog that acts primarily as a reverse transcriptase inhibitor disrupting viral replication by interfering with RNA-dependent DNA polymerase activity It inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with an IC50 value of approximately 0 316 M Lamivudine also suppresses replication of simian retrovirus (SRV-1 and SRV-2) while exhibiting negligible activity on foamy viruses and amphotropic murine leukemia virus (MLV-A) Due to its antiviral mechanism and dual inhibitory effect against both HIV-1 and hepatitis B virus (HBV) lamivudine is frequently utilized in research involving retroviral infection models particularly HIV-1 and HBV coinfection studies to evaluate viral dynamics antiviral efficacy and biochemical responses
Selleck Chemical LLC Lamivudine S1706-1g
Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor used for treatment of chronic HBV and HIV/AIDS It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase